The Ankh appears in the Tomb level of the first game. The player's objective is to enter the Tomb and find the Ankh, thereby stopping the Cultists from completing their ritual. It also appears as the BagTag/Knockout item for the Tomb level, and is available as a story mode pick-up item in the TimeSplitters 2 Mapmaker.

The Ankh resembles Egyptian real life Ankhs, or "Crosses of Life". In the game, this is a simple gold cross with a loop on the top part instead of an upward pointing line. In the game, the ankh is actually shown horizontally.

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